All Shared Cases

Author: sholzma1
Date: Thu, 08/26/2021 - 08:36
NRTI sparing regimen in someone failing Biktarvy

I have a 43 year old man with CKD (stage IV, prior Cr ~3), treated HCV and HIV (on Biktarvy) who presented after a year w/o follow-up and found to have progressive renal failure, Cr 11. Admitted for initiation of HD. Reports compliance with… Read full case

Author: Ncwhelan3
Date: Thu, 07/22/2021 - 16:20
ARV regimen change for 27 y.o. with congenital HIV

27 year old female not taking ART's for the last 5 months. The last ART Genvoya caused excessive nausea. She was well controlled on Bictegravir prior however developed apraxia of speech and right-sided muscle weakness. Although neurological… Read full case

Author: maunank
Date: Thu, 05/13/2021 - 09:18
HIV/TB, INSTI resistance

40 year old patient with HIV, treatment experienced (prior history of TDF/FTC+RAL, TDF/FTC+RAL+ATVc), off ART for > 1 year, current genotype without resistance (but history of M184V and T97A), newly diagnosed with pulmonary TB.  Started on… Read full case

Author: maunank
Date: Thu, 05/13/2021 - 09:12
HIV/TB, INSTI resistance

40 year old patient with HIV, treatment experienced (prior history of TDF/FTC+RAL, TDF/FTC+RAL+ATVc), off ART for > 1 year, current genotype without resistance (but history of M184V and T97A), newly diagnosed with pulmonary TB.  Started on… Read full case

Author: MatthewHamill
Date: Sun, 02/07/2021 - 16:39
HBV/HCV/HIV M184V. Dolutegravir allergy

59yr old AA man. HIV since at least 2004. 

- On Dar/c and Descovy consistently for 13 months.

New onset of renal dysfunction - creat 2.1; eGFR 39 (Jan 2021). 

Previous creats 1.1 - 1.4; eGFR >63. May 2020 Creat 1.4, eGFR… Read full case

Author: maunank
Date: Tue, 12/01/2020 - 20:05
ATV/c with BIC

Patient with extensive treatment history and resistance.

DHHS and Liverpool suggest BIC should 'not be coadministered' with ATV/c due to increase of 300% in exposure. However there were no grade 3-4 toxicities in the ATV-BIC drug drug… Read full case

Author: nicky.mehtani
Date: Tue, 11/03/2020 - 17:31
Phenobarbital + ART

A patient with poorly controlled ART (CD4 145, VL 100k, intermittent adherence to DRV/c/TAF/FTC) and alcohol use disorder was admitted to the hospital in alcohol withdrawal and loaded with phenobarbital for management of withdrawal symptoms. ID… Read full case

Author: oidesous
Date: Thu, 10/15/2020 - 11:31
52 YO caucasian female with WT gain complaint

52 YO Caucasian female who reports 60 pound weight gain over the course of 3 years on Genvoya and Prezista regimen.  She feels strongly that it is medication related. She stopped Prezista on her own over a month ago as she "looked on the internet… Read full case

Author: t.hedley133
Date: Mon, 07/27/2020 - 02:22
Multiclass resistant, salvage therapy, RPR1:16

Previously poorly controlled HIV/AIDS due to non-compliance leading to treatment failure. Genotype showed multi-class resistance, including NRTIs and INSTIs. Patient was started on DTG/ETR/DRV/r on 1 year ago. Patient reports compliance with… Read full case

Author: maunank
Date: Fri, 06/05/2020 - 22:15
LLV with resistance

52 y/o diagnose dx 30 years ago:

ZDV/3TC, then ZDV/3TC/NVP, later TDF/FTC/EFV-->K103N, M184V, Y181C, D67N

Later RAL, ETR, TDF/FTC (didn't want DRV)-->generaly suppressed, but occasional LLV.  Develops N155H.  He wants a once/… Read full case